Implantation of human albumin bone block in the right upper molar region following tissue expansion

The surgery was performed by Dr. Gábor Benedek, MSc in Implantology & Dental Surgery, specialist in preservative dentistry and prosthodontics, dentoalveolar surgeon at Dentha Dentistry, Szeged (Hungary).

Dental arch correction with the fixation of a cortical plate and human cancellous granules

The surgery was performed by Dr. Gábor Benedek, MSc in Implantology & Dental Surgery, specialist in preservative dentistry and prosthodontics, dentoalveolar surgeon at Dentha Dentistry, Szeged (Hungary).

The extraction of the left upper number 5 tooth of the patient was followed by implantation 4 months later; the buccal bony wall seemed maintained at that time. Mild buccal recession was observed in the prosthetic phase but it did not disturb the patient. Later, though, the patient asked for the correction of the bony wall. The position of the implant was good and therefore only the crown was removed. A human cortical plate was fixed on the buccal surface during the remodeling of the bone; the remaining part was filled with human cancellous granules.

Sinus lift with immediate implant placement

The surgery was performed by Dr. Gábor Benedek, MSc in Implantology & Dental Surgery, specialist in preservative dentistry and prosthodontics, dentoalveolar surgeon at Dentha Dentistry, Szeged (Hungary).

2021

Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products

Authors: Otahal A, Kuten-Pella O, Kramer K, Neubauer M, Lacza Z, Nehrer S, De Luna A.Sci Rep. 2021 Mar 12;11(1):5823. doi: 10.1038/s41598-021-84234-5.PMID: 33712660 Free PMC article.

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Characterization and Chondroprotective Effects of Extracellular Vesicles From Plasma- and Serum-Based Autologous Blood-Derived Products for Osteoarthritis Therapy

Authors: Otahal A, Kramer K, Kuten-Pella O, Weiss R, Stotter C, Lacza Z, Weber V, Nehrer S, De Luna A.Front Bioeng Biotechnol. 2020 Sep 25;8:584050. doi: 10.3389/fbioe.2020.584050. eCollection 2020.PMID: 33102466 Free PMC article.

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Comparison between Micro-Computed Tomography and Cone-Beam Computed Tomography in the Assessment of Bone Quality and a Long-Term Volumetric Study of the Augmented Sinus Grafted with an Albumin Impregnated Allograft

Authors: Kivovics M, Szabó BT, Németh O, Iványi D, Trimmel B, Szmirnova I, Orhan K, Mijiritsky E, Szabó G, Dobó-Nagy C.J Clin Med. 2020 Jan 21;9(2):303. doi: 10.3390/jcm9020303.PMID: 31973237 Free PMC article.

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Crosslinked Hyaluronic Acid Gels with Blood-Derived Protein Components for Soft Tissue Regeneration.

Authors: Hinsenkamp A, Ézsiás B, Pál É, Hricisák L, Fülöp Á, Besztercei B, Somkuti J, Smeller L, Pinke B, Kardos D, Simon M, Lacza Z, Hornyák I.Tissue Eng Part A. 2020 Sep 29. doi: 10.1089/ten.TEA.2020.0197. Online ahead of print.PMID: 32854588

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Albumin-impregnated bone granules modulate the interactions between mesenchymal stem cells and monocytes under in vitro inflammatory conditions

Authors: Mijiritsky E, Gardin C, Ferroni L, Lacza Z, Zavan B.Mater Sci Eng C Mater Biol Appl. 2020 May;110:110678. doi: 10.1016/j.msec.2020.110678. Epub 2020 Jan 21.PMID: 32204105

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Albumin-Impregnated Allograft Filling of Surgical Extraction Sockets Achieves Better Bone Remodeling Than Filling with Either Blood Clot or Bovine Xenograft

Authors: Simonffy L, Minya F, Trimmel B, Lacza Z, Dobo-Nagy C.Int J Oral Maxillofac Implants. 2020 Mar/Apr;35(2):297-304. doi: 10.11607/jomi.7554.PMID: 32142566 Clinical Trial.

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The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Locations

Authors: Neubauer M, Kuten O, Stotter C, Kramer K, De Luna A, Muellner T, Lacza Z, Nehrer S.Stem Cells Int. 2019 Dec 31;2019:1358267. doi: 10.1155/2019/1358267. eCollection 2019.PMID: 32082382 Free PMC article.

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Ketamine decreases cell viability of bone explants and impairs bone healing in rats

Authors: Horváthy DB, Szántó P, Marschall B, Bagó M, Csery M, Hornyák I, Doros A, Lacza Z.J Orthop Surg Res. 2020 Feb 11;15(1):46. doi: 10.1186/s13018-020-1579-x.PMID: 32046745 Free PMC article.

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Investigation of Cytokine Changes in Osteoarthritic Knee Joint Tissues in Response to Hyperacute Serum Treatment

Authors: Kardos D, Marschall B, Simon M, Hornyák I, Hinsenkamp A, Kuten O, Gyevnár Z, Erdélyi G, Bárdos T, Paukovits TM, Magos K, Béres G, Szenthe K, Bánáti F, Szathmary S, Nehrer S, Lacza Z.Cells. 2019 Aug 3;8(8):824. doi: 10.3390/cells8080824.PMID: 31382623 Free PMC article.

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2019

The composition of hyperacute serum and platelet-rich plasma is markedly different despite the similar production method

Authors: Dorottya Kardos, Melinda Simon, Gabriella Vácz, Adél Hinsenkamp, Tünde Holczer, Domonkos Cseh, Adrienn Sárközi, Kálmán Szenthe, Ferenc Bánáti, Susan Szathmary, Stefan Nehrer, Olga Kuten, Mariana Masteling, Zsombor Lacza and István Hornyák

Published: 8 Február 2019

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Serum albumin‐coated bone allograft (bonealbumin) results in faster bone formation and mechanically stronger bone in aging rats

Authors: Dénes B. Horváthy, Károly Schandl, Charlotte M. Schwarz, Károly Renner, István Hornyák, Bence T. Szabó, Eugenia Niculescu‐Morzsa, Stefan Nehrer, Csaba Dobó‐Nagy, Attila Doros, Zsombor Lacza

Published: 9 Január 2019

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2018

Microarchitecture of the augmented bone following sinus elevation with an albumin impregnated demineralized freeze-dried bone allograft (bonealbumin) versus anorganic bovine bone mineral: a randomized prospective clinical, histomorphometric, and micro-computed tomography study

Authors: Kivovics Márton, Szabó Bence Tamás, Németh Orsolya, Czinkóczky Béla, Dőri Ferenc, Nagy Péter, Dobó-Nagy Csaba, Csönge Lajos, Lacza Zsombor, Mijiritsky Eitan and Szabó György

Published: Materials (MDPI) 2018,11,202 https://doi.org/10.3390/ma11020202

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Immediate implant placement by using bone-albumin allograft and concentrated growth factors (cgfs): preliminary results of a pilot study

Authors: F. Inchingolo, A. Ballini, P.G. Georgakopoulos, A.D. Inchingolo, S. Tsantis, D. De Vito, S. Cantore, I.P. Georgakopoulos, G. Dipalma

Published: ORAL & Implantology – Anno XI – N. 1/2018

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2017

Serum albumin as a local therapeutic agent in cell therapy and tissue engineering

Authors: Dénes B. Horváthy et al; Institute of Clinical Experimental Research, Semmelweis University, Budapest, Hungary

Published: Wiley Online Library – BioFactors | DOI: 10.1002/biof.1337 | 11 November 2016

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Localized maxillary ridge augmentation with mineralized plasmatic matrix for dental implant placement

Authors: Ahmed Halim Ayoub, President of the Egyptian Society of Oral Implantology, Alexandria, Egypt, Faculty of Dentistry – B.P.P. University, London

Published: International Journal of Preventive and Clinical Dental Research | April-June 2017;4(2):1-5

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2016

Bone-albumin filling decreases donor sitemorbidity and enhances bone formation after anterior cruciate ligament reconstruction with bone-patellar tendon-bone autografts

Authors: Károly Schandl, et al; InstituteofClinicalExperimental Research,SemmelweisUniversity & Saint George University Teaching Hospital of County-Fejér

Published: International Orthopaedics (SICOT) (2016) 40:2097–2104 | DOI 10.1007/s00264-016-3246-8 | 29 June 2016

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Clinical and radiographic evaluation of socket prerevation using authologous concentrated growth factors enriched bone graft matrix (sticky bone): a case report

Authors: Ahmed Halim Ayoub, President of the Egyptian Society of Oral Implantology, Alexandria, Egypt, Faculty of Dentistry – B.P.P. University, London

Published: EC Dental Science 5.4 (2016) 1128-1135 31. | October 2016

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2015

Remineralization of demineralized bone matrix in critical size cranial defects in rats: a 6-month follow-up study

Authors: Dénes B. Horváthy et al; Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Hungary

Published: Journal of Biomedical Materials Research Part B: Applied Biomaterial | DOI: 10.1002/jbm.b.33446 | 2. July 2015.

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Serum albumin coating of demineralized bone matrix results in stronger new bone formation

Authors: Dénes B. Horváthy et al; Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Budapest, Hungary

Published: Journal of Biomedical Materials Research Part B: Applied Biomaterials | DOI: 10.1002/jbm.b.33359 | 10. February 2015.

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The use of structural proximal tibial allografts

Authors: Klára, T., Csönge, L., Janositz, G., Pap, K., Lacza, Zs.

Published: Orv. Hetil., 2015, 156(2), 67–70.

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2014

Increase release time of antibiotics

Authors: István Hornyák et al; Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Tűzoltó utca 37-47, Budapest 1094, Hungary

Published: BioMed Research International | DOI: 10.1155/2014/459867 | 19 June 2014.

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2013

Albumin-coated structural lyophilized bone allografts: a clinical report of 10 cases

Authors: Tamás Klára et al; Trauma Department, Erzsébet Teaching Hospital

Published: Cell and Tissue Banking International Journal for Banking, Engineering and Transplantation of Cells and Tissues Incorporating Advances in Tissue Banking | DOI 10.1007/s10561-013-9379-8 | 16 May 2013

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Serum albumin enhances bone healing in a nonunion femoral defect model in rats: a computer tomography micromorphometry study

Authors: Gábor Skaliczki et al; Department of Orthopaedics, Semmelweis University

Published: International Orthopaedics, v.37(4); 2013 Apr | DOI: 10.1007/s00264-012-1770-8 | 15 January 2013

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2012

Freeze-dried human serum albumin improves the adherence and proliferation of mesenchymal stem cells on mineralized human bone allografts

Authors: Miklós Weszl et al; Tissue Engineering Laboratory, Department of Human Physiology and Clinical Experimental Research, Semmelweis University

Published: J Orthop Res. | DOI 10.1002/jor.21527 | 2012 Mar;30(3):489-96

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